Zeneng Wang Selected Research

trimethylamine

1/2022	Gut microbial trimethylamine is elevated in alcohol-associated hepatitis and contributes to ethanol-induced liver injury in mice.
1/2022	Gut microbe-targeted choline trimethylamine lyase inhibition improves obesity via rewiring of host circadian rhythms.
12/2021	Inhibition of microbiota-dependent TMAO production attenuates chronic kidney disease in mice.
1/2019	Genetic Deficiency of Flavin-Containing Monooxygenase 3 ( Fmo3) Protects Against Thrombosis but Has Only a Minor Effect on Plasma Lipid Levels-Brief Report.
1/2019	l-Carnitine in omnivorous diets induces an atherogenic gut microbial pathway in humans.
1/2016	Choline Diet and Its Gut Microbe-Derived Metabolite, Trimethylamine N-Oxide, Exacerbate Pressure Overload-Induced Heart Failure.
12/2015	Non-lethal Inhibition of Gut Microbial Trimethylamine Production for the Treatment of Atherosclerosis.
1/2015	Flavin containing monooxygenase 3 exerts broad effects on glucose and lipid metabolism and atherosclerosis.
11/2014	γ-Butyrobetaine is a proatherogenic intermediate in gut microbial metabolism of L-carnitine to TMAO.
4/2014	Prognostic value of choline and betaine depends on intestinal microbiota-generated metabolite trimethylamine-N-oxide.

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Zeneng Wang Research Topics

Disease

26	Cardiovascular Diseases (Cardiovascular Disease) 01/2022 - 09/2009
24	Atherosclerosis 01/2022 - 04/2011
17	Coronary Artery Disease (Coronary Atherosclerosis) 06/2022 - 10/2007
17	Stroke (Strokes) 01/2022 - 10/2007
15	Myocardial Infarction 01/2022 - 10/2007
14	Inflammation (Inflammations) 01/2022 - 10/2007
11	Heart Failure 04/2022 - 03/2012
10	Thrombosis (Thrombus) 01/2022 - 03/2016
7	Obesity 01/2022 - 01/2017
7	Systolic Heart Failure 02/2015 - 10/2008
6	Atherosclerotic Plaque (Atheroma) 01/2022 - 10/2007
6	Fibrosis (Cirrhosis) 12/2021 - 01/2015
4	Acute Coronary Syndrome 01/2022 - 03/2017
4	Type 2 Diabetes Mellitus (MODY) 01/2021 - 01/2017
4	Heart Diseases (Heart Disease) 10/2018 - 04/2011
4	Neoplasms (Cancer) 01/2017 - 07/2013
4	Left Ventricular Dysfunction 02/2015 - 10/2008
3	Non-alcoholic Fatty Liver Disease 04/2022 - 01/2017
3	Insulin Resistance 04/2022 - 01/2019
3	Chronic Renal Insufficiency 12/2021 - 01/2015
3	Hypertension (High Blood Pressure) 01/2020 - 10/2012
3	Diabetes Mellitus 01/2020 - 02/2015
3	Asthma (Bronchial Asthma) 10/2018 - 10/2008
2	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 08/2021 - 01/2019
2	Peripheral Arterial Disease 01/2020 - 10/2016
2	Chest Pain (Chest Pains) 01/2019 - 03/2017
2	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2018 - 01/2017
2	Renal Insufficiency (Renal Failure) 01/2018 - 01/2015
2	Chronic Kidney Failure (Chronic Renal Failure) 04/2013 - 10/2007
2	Pulmonary Hypertension 03/2012 - 05/2009
1	Synucleinopathies 01/2022
1	Multiple System Atrophy 01/2022
1	Dyslipidemias (Dyslipidemia) 01/2022
1	Hepatitis 01/2022

Drug/Important Bio-Agent (IBA)

61	trimethyloxamine (trimethylamine N-oxide)IBA 06/2022 - 04/2011
26	Choline (Choline Chloride)IBA 01/2022 - 04/2011
14	Carnitine (L-Carnitine)FDA LinkGeneric 01/2022 - 05/2013
11	trimethylamineIBA 01/2022 - 05/2013
10	Betaine (C.B.B.)FDA Link 01/2022 - 04/2011
9	omega-Chloroacetophenone (Mace)IBA 01/2022 - 06/2009
9	Proteins (Proteins, Gene)FDA Link 01/2017 - 10/2007
8	dimethylaniline monooxygenase (N-oxide forming) (flavin-containing monooxygenase)IBA 04/2022 - 01/2013
8	Biomarkers (Surrogate Marker)IBA 12/2021 - 12/2007
8	Phosphatidylcholines (Phosphatidylcholine)IBA 01/2017 - 04/2011
8	Arginine (L-Arginine)FDA Link 02/2013 - 11/2007
7	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2018 - 11/2007
6	LipidsIBA 01/2022 - 01/2009
6	CitrullineIBA 04/2016 - 10/2008
5	Anti-Bacterial Agents (Antibiotics)IBA 08/2021 - 02/2015
5	homocitrullineIBA 04/2016 - 10/2007
4	Apolipoprotein A-I (Apolipoprotein A1)IBA 01/2022 - 07/2013
4	Apolipoproteins E (ApoE)IBA 12/2021 - 01/2016
4	Glucose (Dextrose)FDA LinkGeneric 01/2021 - 01/2015
4	Brain Natriuretic Peptide (Natrecor)FDA Link 01/2020 - 04/2013
4	pro-brain natriuretic peptide (1-76)IBA 01/2020 - 04/2013
4	Urea (Carbamide)FDA LinkGeneric 01/2019 - 10/2008
3	LyasesIBA 01/2022 - 10/2018
3	Fatty Acids (Saturated Fatty Acids)IBA 01/2022 - 06/2013
3	Glycine (Aminoacetic Acid)FDA LinkGeneric 01/2021 - 01/2016
3	Bile Acids and Salts (Bile Acids)IBA 01/2021 - 01/2017
3	C-Reactive ProteinIBA 01/2020 - 04/2013
3	CholesterolIBA 01/2019 - 02/2014
3	LDL Receptors (LDL Receptor)IBA 01/2019 - 01/2015
3	Antisense OligonucleotidesIBA 01/2019 - 01/2015
3	symmetric dimethylarginineIBA 01/2018 - 10/2008
3	Peroxidase (Myeloperoxidase)IBA 02/2014 - 10/2007
3	N,N-dimethylarginine (asymmetric dimethylarginine)IBA 03/2012 - 10/2008
3	OrnithineIBA 03/2012 - 10/2008
2	Volatile Fatty AcidsIBA 01/2022 - 01/2018
2	Phenylalanine (L-Phenylalanine)FDA Link 01/2022 - 04/2016
2	Lysine (L-Lysine)FDA Link 01/2022 - 04/2013
2	Cystatin CIBA 12/2021 - 04/2013
2	CreatinineIBA 12/2021 - 04/2016
2	Insulin (Novolin)FDA Link 01/2021 - 01/2019
2	gamma-butyrobetaine (butyrobetaine)IBA 01/2021 - 01/2019
2	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 01/2020 - 10/2018
2	trimethyllysineIBA 01/2019 - 01/2018
2	CytokinesIBA 01/2018 - 10/2016
2	ArginaseIBA 01/2018 - 10/2008
2	EnzymesIBA 01/2017 - 01/2017
2	LecithinsIBA 01/2015 - 04/2013
2	HDL LipoproteinsIBA 02/2014 - 07/2013
2	Natriuretic PeptidesIBA 07/2013 - 02/2013
2	Oxidants (Oxidizing Agents)IBA 04/2013 - 12/2007
2	CyanatesIBA 04/2013 - 10/2007
2	Nitric Oxide Synthase (NO Synthase)IBA 03/2012 - 05/2009
1	Hormones (Hormone)IBA 04/2022
1	Environmental Pollutants (Pollutants, Environmental)IBA 04/2022
1	DioxinsIBA 04/2022
1	caprylic aldehydeIBA 01/2022
1	Interleukin-1 (Interleukin 1)IBA 01/2022
1	Odorant Receptors (Odorant Receptor)IBA 01/2022
1	Succinic Acid (Succinate)IBA 01/2022
1	CarbonIBA 01/2022
1	Adrenergic Agents (Adrenergic Drugs)IBA 01/2022
1	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2022
1	Atorvastatin (Lipitor)FDA Link 01/2022

Therapy/Procedure

7	Therapeutics 01/2022 - 02/2013
5	Transplantation 01/2022 - 04/2013
1	Dual Anti-Platelet Therapy 01/2022